
The topic of CDC employees and vaccination status has been a highly contested issue, with political interference, vaccine misinformation, and violence impacting the agency. CDC employees have faced layoffs and leadership changes, with former Health and Human Services Secretary Robert F. Kennedy Jr. facing calls for his resignation or firing from over a thousand current and former employees. The dispute centres around Kennedy's anti-vaccine views, with employees expressing despair and concern about the impact on public health. Vaccine advisory boards have been reshuffled, and funding for mRNA vaccine research has been cut. The CDC's response to the COVID-19 pandemic has been criticized, and employees have been caught in political fights over vaccines. The recent shooting at CDC headquarters by an individual with discontent over the COVID-19 vaccine has further exacerbated the situation.
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What You'll Learn

CDC employees call for Robert F. Kennedy Jr.'s resignation
In 2025, Robert F. Kennedy Jr., the Secretary of Health and Human Services, faced backlash for his handling of the CDC and its policies. More than 1,000 current and former employees of the Department of Health and Human Services (HHS) called for Kennedy's resignation, citing actions that endangered public health and politicized the agency. This demand came after Kennedy's controversial decision to oust CDC Director Susan Monarez, which resulted in the resignation of several senior CDC officials.
Kennedy defended his actions, stating that changes at the CDC were necessary due to its performance during the COVID-19 pandemic. He denied pressuring Monarez to pre-approve vaccine recommendations and accused her of lying about her firing. However, Kennedy admitted to demanding that Monarez fire career scientists or public health experts at the CDC. The acting CDC director, Jim O'Neil, was also present during a meeting regarding this issue.
The letter from HHS employees highlighted concerns about Kennedy's personnel decisions and the erosion of scientific integrity within the agency. They emphasized that health policies should be based on evidence-based principles rather than partisan politics. The letter also mentioned Kennedy's appointment of "political ideologues" and his verbal attacks on his agency's workforce. Additionally, the letter referenced the broader petition organized by Save HHS, which had drawn thousands of signers.
The turmoil at the CDC and Kennedy's leadership sparked reactions from various individuals and entities. Three Democratic governors from California, Oregon, and Washington created the West Coast Health Alliance to protect public health and ensure science-driven decision-making. Kennedy's family members, including his sister Kerry Kennedy and nephew Joseph P. Kennedy III, also called for his resignation, stating that he posed a threat to Americans' health.
The situation at the CDC and Kennedy's role in it caused concern among lawmakers, scientists, and former agency employees. The mass firing of CDC doctors and scientists by President Trump and the politicization of the agency were seen as a direct assault on the health and safety of Americans. The White House's involvement in forcing out Monarez, who clashed with Kennedy over federal vaccine policies, further exacerbated the issues.
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Political interference at the CDC
The US Centers for Disease Control and Prevention (CDC) has faced significant political interference, particularly during the Trump administration. This interference has led to concerns about the credibility and effectiveness of the CDC, with experts warning that politicisation could have life-threatening consequences.
One notable incident of political interference occurred in 2025, when Health and Human Services Secretary Robert F. Kennedy Jr. fired CDC Director Susan Monarez just weeks after her confirmation. Monarez had clashed with Kennedy over his efforts to reshape federal vaccine policies, particularly COVID-19 vaccines, in ways that contradicted established scientific research. Kennedy defended the firing, stating that changes at the CDC were "absolutely necessary" due to its handling of the COVID-19 pandemic. However, the decision prompted protests from CDC staff, resignations of senior officials, and bipartisan criticism in Congress.
Kennedy has also been accused of politicising the CDC's vaccine advisory committees by appointing individuals who share his anti-vaccine views. In June 2025, he removed all 17 members of the CDC's Advisory Committee on Immunization Practices, a group central to vaccine safety oversight. This action was condemned by Democratic governors of California, Oregon, and Washington, who formed the West Coast Health Alliance to protect science-driven decision-making in public health.
The CDC has historically been perceived as an apolitical agency, but the appointment of political loyalists to leadership positions has sparked warnings of its growing politicisation. Experts warn that installing individuals who lack strong public health credentials risks eroding the CDC's credibility and could lead to the dissemination of misinformation. The acting director of the CDC is a former biotech investor, while the chief of staff and chief operating officer are lawyers, marking a significant departure from the norm.
The politicisation of the CDC has had tangible impacts on public health policy. For example, Florida's state surgeon general announced that children would no longer be required to receive vaccines for preventable diseases, and Idaho passed a similar law. These decisions have been criticised by public health officials, who warn of an erosion of trust in vaccines and the potential for negative health consequences.
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Layoffs at the CDC
The US Department of Health and Human Services (HHS) announced in March 2025 that it would lay off 10,000 employees, including 2,400 people at the CDC. This was part of a broad reorganisation effort to reduce "bureaucratic sprawl" and refocus the agency on "reversing the chronic disease epidemic".
The CDC has been in turmoil for months, with mass layoffs, directives, and political interference. In April 2025, the Trump administration began issuing dismissal notices as part of the broad reorganisation effort. The CDC has rarely experienced this level of interference from Washington, with employees caught in the crosshairs of a political fight over vaccines.
The mass layoffs have been criticised by Democratic lawmakers, who argue that they weaken the broader public health infrastructure and delay critical responses to health threats. Local health departments rely on CDC support, and with fewer resources and less staff, the ripple effects could be significant.
In addition to the layoffs, several senior officials at the CDC have resigned in protest of the leadership's handling of vaccine policies and the removal of Susan Monarez as director. Monarez clashed with Robert F. Kennedy Jr., the secretary of the US health and human services department (HHS), over his efforts to reshape federal vaccine policies in ways that contradict established scientific research. Kennedy has defended the changes, saying they were "absolutely necessary" due to the CDC's performance during the COVID-19 pandemic.
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Violence against CDC employees
On 9 August 2025, a man opened fire at the US Centres for Disease Control and Prevention headquarters in Atlanta, Georgia. The shooter, who was identified as having blamed the COVID-19 vaccine for making him depressed and suicidal, unleashed a barrage of gunfire, leaving bullet marks across the campus. At least four CDC buildings were hit, and more than 500 shell casings were recovered. The attack resulted in the death of a police officer, David Rose, and the shooter, whose death was due to a self-inflicted gunshot wound.
The American Federation of Government Employees, Local 2883, has emphasised the need for federal officials to take a clear stance against vaccine disinformation to prevent violence against scientists. They have specifically called out Health and Human Services Secretary Robert F. Kennedy Jr. for his continuous lies about vaccine safety, which have fuelled a hostile climate of mistrust. Public health leaders have experienced harassment and violence across the country due to the rise of anti-vaccine sentiment during the pandemic.
In the aftermath of the attack, HHS Communications Director Andrew Nixon stated that Kennedy condemned the horrific incident and was committed to ensuring the safety of CDC employees. However, critics have argued that Kennedy's actions, such as abruptly removing all 17 members of the CDC's Advisory Committee on Immunization Practices, have contributed to the politicisation of the agency and endangered public health.
The shooting has highlighted the growing turmoil within the CDC, with mass firings, resignations, and protests occurring in the wake of Kennedy's controversial leadership decisions. The violence has also impacted the mental health of CDC employees, with the union recommending that staffers not be forced to return to work immediately after such a traumatic event.
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The CDC's response to the COVID-19 pandemic
The CDC has faced criticism for its response to the COVID-19 pandemic, with some calling for an overhaul of the agency. The CDC has been accused of being slow to act and not adequately protecting the health and safety of Americans during the pandemic. This criticism resulted in the mass firing of CDC doctors and scientists by President Trump, which further weakened the agency.
During the pandemic, the CDC faced further challenges with the appointment of Robert F. Kennedy Jr. as the Secretary of Health and Human Services. Kennedy has been accused of politicising the agency and pushing his own anti-vaccine agenda. He clashed with the former director of the CDC, Susan Monarez, who refused to accept the recommendations from the CDC's vaccine advisory committee, which was stacked with appointees sharing Kennedy's anti-vaccine views. Monarez's expulsion triggered a mass walkout of staff and further weakened the agency.
In defence of his actions, Kennedy stated that changes at the CDC were "absolutely necessary" due to its performance during the COVID-19 pandemic. He also denied pressuring Monarez to pre-approve vaccine recommendations. Kennedy has faced heated questions and criticism from lawmakers, scientists, and former agency employees, who argue that his actions have endangered the nation's health and left the CDC in a state of chaos.
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