Madison Clarke
On April 21, 2021, the Indian government released data on the number of people who tested positive for COVID-19 after receiving their first and second doses of the Covishield vaccine. The data showed that over 21,000 people tested positive after the first dose, while 5,014 people tested positive after the second dose, out of 1,57,32,754 individuals. This equates to 0.03% of people testing positive after the second dose, a percentage deemed \very low\ by experts. Despite this low risk of infection, people are still advised to follow COVID-appropriate behaviour after vaccination, such as social distancing, masking, and hand hygiene.
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What You'll Learn
- A small percentage test positive after the second dose
- Vaccines reduce the risk of infection and prevent severe infection
- The proportion of people testing positive is lower among the general population
- Immunity is not absolute, so social distancing and masking should continue
- The time duration between the two doses can determine the vaccine's efficacy
A small percentage test positive after the second dose
A small percentage of people have tested positive for COVID-19 after receiving their second dose of the Covishield vaccine. Data released by the Indian government in April 2021 revealed that out of 1,57,32,754 individuals who received their second dose of Covishield, 5,014 (0.03%) contracted the infection. This data includes healthcare workers and frontline workers, who are considered high-risk populations. Experts have emphasised that these percentages are very low and not a cause for worry.
It is important to note that breakthrough infections, which occur when an individual gets infected after being vaccinated, can still happen. However, vaccines significantly reduce the risk of infection and prevent severe disease and death. Even if vaccinated individuals get infected, the chances of developing a severe form of the disease are much lower.
In the case of Covishield, the time duration between the two doses can also impact its efficacy. The Union Cabinet in India declared that the second dose of Covishield should be administered between 4 to 8 weeks after the first dose for greater effectiveness. This decision was based on recommendations from the National Technical Advisory Group on Immunization (NTAGI) and the National Expert Group on Vaccine Administration for Covid-19 (NEGVAC).
While Covishield has shown an efficacy of around 70%, it is important to maintain COVID-appropriate behaviour even after vaccination. This includes social distancing, masking, and hand hygiene. Additionally, individuals who test positive for COVID-19 after their first vaccine dose should wait for at least four weeks after recovery before taking the second dose.
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Vaccines reduce the risk of infection and prevent severe infection
Vaccines are safe and highly effective in protecting people from severe illness, hospitalisation, and death. They reduce the risk of infection and prevent severe infection. For instance, the 2025-2026 COVID-19 and flu vaccines are expected to reduce severe illness, hospitalisations, and deaths from respiratory viruses, which usually peak in the U.S. during late fall and winter.
In April 2021, the Indian government released data showing that 0.03% of 1,57,32,754 people who took the second dose of Covishield, contracted the infection. This is a very small number and not worrisome, according to NITI Aayog Member (Health) V K Paul. He further stressed that there is a risk of infection even after vaccination, so it is important to follow COVID-appropriate behaviour.
The data also showed that the proportion of people testing positive was 0.02% after the first dose and 0.03% after the second dose of Covishield. Experts believe that the percentage of people testing positive after vaccination would be even lower among the general population.
While vaccines provide excellent protection, it is important to note that even if people get infected after vaccination, the severity of the disease is reduced. Covishield, for instance, has an efficacy of around 70%, and sufficient antibodies are generated only 10-15 days after the second dose. Therefore, it is crucial to follow preventive measures and maintain COVID-appropriate behaviour even after vaccination to minimise the risk of infection.
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The proportion of people testing positive is lower among the general population
On April 21, 2021, the Indian government released data on the number of people who tested positive for COVID-19 after receiving their first and second doses of the Covishield vaccine. The data revealed that more than 21,000 people tested positive after the first dose, while over 5,000 contracted the infection after the second dose. Experts have stated that the percentage of such cases is "very low".
Among the 1,57,32,754 individuals who received the second dose of Covishield, only 5,014 (0.03%) contracted the infection. This percentage is even lower for the general population, as the data is based primarily on high-risk healthcare workers and frontline workers. Dr VK Paul emphasised that the proportion of people testing positive after vaccination would likely be lower among the general public.
Furthermore, NITI Aayog Member (Health) V K Paul noted that the risk of infection remains even after vaccination. He advised individuals to continue following COVID-appropriate behaviour, such as social distancing, masking, and hand hygiene, even after receiving the vaccine. This is because the protection conferred by vaccines is not absolute, and breakthrough infections can still occur, albeit at a lower rate.
While the Covishield vaccine has an efficacy of around 70%, it is important to note that sufficient antibodies are typically generated only 10-15 days after the second dose. Additionally, the time duration between the two doses can impact the vaccine's efficacy. The Union Cabinet declared that the ideal interval between the first and second doses of Covishield is 4 to 8 weeks for greater effectiveness.
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Immunity is not absolute, so social distancing and masking should continue
Vaccines are designed to provide resistance to diseases. In the case of COVID-19 vaccines, they have shown better efficacy in preventing people from falling sick. However, immunity is not absolute, and there are recorded cases of individuals contracting COVID-19 even after receiving both doses of the Covishield vaccine. Covishield, also known as the Oxford-AstraZeneca vaccine, is produced locally by the Serum Institute of India. It is made from a weakened version of the common cold adenovirus from chimpanzees, modified to resemble the coronavirus.
The vaccine is administered in two doses, with the second dose coming between four and twelve weeks after the first. Clinical trials of the vaccine showed an efficacy of 90% when individuals received a half dose first and then a full dose. The overall efficacy of the vaccine increases when there is a longer gap between the first and second doses, with an efficacy of 70% after the first dose.
Despite the vaccine's efficacy, a small number of vaccinated individuals may still get infected with COVID-19. Data from the Indian Council of Medical Research (ICMR) shows that over 21,000 people tested positive for COVID-19 after receiving the first dose of Covishield, while more than 5,500 contracted the infection after taking the second dose. This accounts for 0.03% of individuals who received their second dose, a very small number that is not considered worrisome.
Even with vaccination, it is important to continue practicing social distancing and wearing masks to protect oneself and others. Vaccinated individuals should take necessary precautions, especially when interacting with unvaccinated people who are more prone to developing the infection. It is advisable to avoid crowded areas and maintain a social distance of at least 6 feet from others. While the vaccines provide protection, they are not a guarantee against infection, and following COVID-appropriate behavior is crucial even after vaccination.
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The time duration between the two doses can determine the vaccine's efficacy
The Covishield vaccine is one of the two COVID-19 vaccines that the Government of India has granted emergency use authorisation for. The other is Covaxin. Both vaccines are being used for the government's vaccination drive.
The Covishield vaccine is a two-dose regimen, and the time duration between the two doses can determine the vaccine's efficacy. The Union Cabinet, based on advice from the task force on COVID, decided that the second dose of Covishield should be administered between four to eight weeks after the first dose for greater effectiveness. This decision was made after the National Technical Advisory Group on Immunization (NTAGI) and the National Expert Group on Vaccine Administration for Covid-19 (NEGVAC) revealed that the time duration between the two doses could determine the vaccine's efficacy. The groups declared that the second dose of Covishield must be administered either four weeks or eight weeks at most after the first dose.
Studies suggest that COVID vaccines are most effective in the first few months after the shot. This is why health experts usually recommend updated doses or boosters three to four months after the last COVID shot. COVID vaccines train the immune system to fight off COVID-19 infections by giving the body a set of instructions to make a harmless piece of the virus. Vaccines can be divided into two general categories: live or non-live. Most live vaccines used in the United States are "live attenuated", meaning that the microbe in the vaccine is alive but has been weakened. One live vaccine licensed for use in the United States (oral adenovirus vaccine) is not attenuated. Live vaccines must replicate to induce an immune response, and several factors can interfere with replication. These factors are a driving principle in the timing and spacing of live vaccines.
Data from the Indian Council of Medical Research (ICMR) shows that more than 21,000 people tested positive for COVID-19 after taking the first dose of either Covishield or Covaxin, while over 5,500 contracted the infection after taking the second dose. Experts say the percentage of such people is "very low".
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Frequently asked questions
Yes, it is possible to test positive for COVID-19 after taking the Covishield vaccine.
The likelihood of testing positive after taking the Covishield vaccine is very low. Data shows that 0.03% of people who took the second dose of Covishield contracted the infection.
If you test positive for COVID-19 after taking the first dose of the Covishield vaccine, it is recommended that you wait for at least four weeks after recovering from your COVID symptoms before taking the second dose.
Yes, it is important to continue practising social distancing, masking, and hand hygiene even after taking the Covishield vaccine, as protection conferred by vaccines is not absolute.
