
Polio was once one of the most feared diseases in the United States. However, thanks to successful vaccination programs, it has been eliminated in the country. The best way to protect against polio is to get vaccinated. The polio vaccine provides lifelong immunity, and most adults in the U.S. are presumed to be immune. While two doses of the inactivated polio vaccine (IPV) are 90% effective or more against paralytic polio, three doses are 99% to 100% effective.
| Characteristics | Values |
|---|---|
| Chances of getting polio if vaccinated | Low |
| Chances of getting polio if unvaccinated | High |
| Effectiveness of two doses of IPV | 90% or more |
| Effectiveness of three doses of IPV | 99% to 100% |
| Number of recommended doses for children | 4 |
| Number of recommended doses for unvaccinated adults | 3 |
| Booster dose | Recommended for fully vaccinated individuals at higher risk of polio exposure |
| Duration of protection | Many years |
| Protection for adults vaccinated as children | Likely |
| Protection for unvaccinated adults | Unlikely |
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What You'll Learn
- The polio vaccine provides lifelong immunity
- Two doses of the IPV polio vaccine are 90% effective against paralytic polio
- Three doses of the IPV polio vaccine are 99-100% effective
- The oral polio vaccine is still used in many parts of the world
- The risk of polio in the US is extremely low due to high vaccination rates

The polio vaccine provides lifelong immunity
The polio vaccine has been a part of routine childhood immunization in the United States for decades, and it has successfully protected most people in the country from the disease. While polio was once one of the most feared diseases in the United States, the vaccine has eliminated the wild poliovirus within the country. This success is largely due to the widespread vaccination of children, who are now protected from polio for life.
While the oral polio vaccine (OPV), which uses a weakened form of the live poliovirus, is still used in many other parts of the world, it is no longer licensed or available in the United States due to the risk of poliovirus variants. However, both types of vaccines offer protection against all polio strains, including mutated strains that may arise from low vaccination rates.
It is important to note that while the polio vaccine provides lifelong immunity, booster doses may be recommended for adults who completed their polio vaccination series as children but are at higher risk of polio exposure. These individuals can receive one lifetime IPV booster dose to ensure continued protection against the disease.
Overall, the polio vaccine has been a remarkable success story in public health, providing lifelong immunity to those who receive the full series of recommended doses and effectively eliminating the wild poliovirus in the United States.
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Two doses of the IPV polio vaccine are 90% effective against paralytic polio
The best protection against polio is to get vaccinated. The polio vaccination has been part of the routine childhood immunization schedule in the United States for decades, and it is still part of the schedule today. Inactivated polio vaccine (IPV) is the only polio vaccine that has been administered in the United States since 2000.
The World Health Organization (WHO) recommends that all children be fully vaccinated against polio. The two vaccines, IPV and OPV, have eliminated polio from most of the world and reduced the number of cases reported each year from an estimated 350,000 in 1988 to 33 in 2018.
In countries with high levels of coverage and low risks of importation and transmission, the WHO recommends a primary series of three IPV injections, with a booster dose after an interval of six months or more if the first dose was given before two months of age.
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Three doses of the IPV polio vaccine are 99-100% effective
Vaccination is the best way to protect against polio. Inactivated polio vaccine (IPV) is the only polio vaccine that has been administered in the United States since 2000. It is given by shot in the leg or arm, depending on the patient's age. IPV is highly effective in preventing polio, and three doses of the vaccine offer 99-100% protection against paralytic polio.
The CDC recommends that children receive four doses of IPV, with the last dose administered after four years of age and at least six months after the previous dose. This vaccination schedule is designed to provide maximum protection against the disease. While two doses of IPV are 90% effective or more against paralytic polio, receiving three doses boosts the protection to 99%.
Completing the primary series of three or more doses of IPV is crucial for full vaccination status. While mild side effects, such as soreness at the injection site, may occur, IPV is generally safe and has not been known to cause serious problems. It is essential to get all recommended doses for optimal protection against polio.
In addition to routine childhood immunization, adults who have not completed their polio vaccination or are at increased risk of exposure can receive the necessary doses or a lifetime booster dose of IPV. This is particularly important for those travelling to areas with a higher risk of polio exposure or working in healthcare settings where they may handle poliovirus specimens.
The success of polio vaccination programs has led to the elimination of wild poliovirus in the United States. However, it is important to maintain high vaccination rates to protect against the reintroduction of the disease from other countries. IPV has played a crucial role in preventing polio and reducing the risk of vaccine-derived poliovirus, making it a highly effective tool in the fight against this once-feared disease.
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The oral polio vaccine is still used in many parts of the world
The oral polio vaccine (OPV) is a live attenuated vaccine that is produced by passing the virus through non-human cells at sub-physiological temperatures, causing spontaneous mutations in the viral genome. OPV was first successfully demonstrated by Hilary Koprowski in 1950, but his vaccine was not approved for use in the United States. Another oral polio vaccine, developed by Albert Sabin, came into commercial use in 1961 and was chosen for worldwide distribution.
The United States stopped using OPV in 2000 and now exclusively uses the inactivated polio vaccine (IPV), which is administered via injection in the leg or arm. This switch was made to eliminate the risk of polio variants that can occur with OPV. However, OPV is still used in many other parts of the world. Children in these countries receive the vaccine by drops in the mouth.
OPV has been crucial in the effort to eradicate polio worldwide. Until recently, a trivalent OPV containing all three viral strains was used and had nearly eradicated polio infection globally. However, with the eradication of wild poliovirus type 2, the trivalent OPV was phased out in 2016 and replaced with a bivalent vaccine containing only types 1 and 3. This switch contributed to outbreaks of circulating vaccine-derived poliovirus type 2 (cVDPV2), which increased from two cases in 2016 to 1037 cases in 2020.
Despite these challenges, OPV remains an important tool in the fight against polio. A novel OPV2 vaccine (nOPV2) was granted full licensure in December 2023 and offers improved genetic stability over traditional oral vaccines, reducing the likelihood of reverting to a virulent form. While OPV has been successful in reducing polio cases, it is important to note that polio has never been successfully eliminated from Pakistan or Afghanistan, and cases continue to occur worldwide.
Overall, while OPV is no longer used in the United States, it remains in use in many other countries and is crucial to global polio eradication efforts.
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The risk of polio in the US is extremely low due to high vaccination rates
Polio vaccination has been a part of the routine childhood immunization schedule in the United States for decades. The success of this vaccination program means that most people in the US are protected from polio. In fact, wild poliovirus has been eliminated in the country.
The inactivated polio vaccine (IPV) is the only polio vaccine that has been administered in the US since 2000. Children should receive four doses of the IPV vaccine, with the last dose given after four years of age. Two doses of IPV are 90% effective or more against paralytic polio, while three doses are 99% to 100% effective. Almost all children (over 99%) who receive all recommended doses of the IPV vaccine will be protected from polio.
Although polio has been eliminated in the US, the disease still occurs in other parts of the world. It only takes one infected person travelling from another country to bring polio back into the US. Therefore, it is important to maintain high vaccination rates to protect against polio re-entering the country. People who plan to travel internationally should ensure they are fully vaccinated against polio before departure.
In addition to vaccination, good hand hygiene is important for protecting against polio, as the poliovirus enters the body through the mouth and can be spread through person-to-person contact. However, it is worth noting that alcohol-based hand sanitizers do not kill the poliovirus.
Overall, the risk of polio in the US is extremely low due to high vaccination rates, but maintaining these rates and good hygiene practices is crucial to preventing the re-emergence of the disease.
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Frequently asked questions
Yes, the polio vaccine provides lifelong immunity. Two doses of the inactivated polio vaccine (IPV) are 90% effective or more against paralytic polio, and three doses are 99-100% effective.
Children should get four doses of the polio vaccine, with the last dose administered after the age of four and at least six months after the previous dose. Adults who have never been vaccinated against polio should get three doses of the IPV vaccine.
The best way to protect against polio is to get vaccinated. The polio vaccine has been part of routine childhood immunizations in the United States for decades, and most adults have likely been vaccinated during childhood.
Yes, the polio vaccine is safe and effective in providing protection against polio. It has been used for decades and has successfully eliminated wild poliovirus in the United States.
The polio vaccine offers protection against all polio strains, including mutated ones. However, it is important to follow the recommended vaccination schedule to ensure full protection. People at higher risk of polio exposure may receive a booster dose if needed.











































