
COVID-19 vaccines have been crucial in the fight against the virus. While vaccination does not guarantee that one will not contract COVID-19, it significantly reduces the likelihood and severity of the illness. Vaccinated individuals who experience breakthrough infections typically exhibit milder symptoms, and their risk of hospitalization or death is lower compared to unvaccinated individuals. However, factors such as age, immune system health, and frequent exposure to the virus may influence the chances of contracting COVID-19, even after vaccination. As new variants emerge and immunity wanes over time, staying up to date with vaccinations, including boosters, remains essential to maximize protection. The CDC recommends that most adults aged 18 and older receive the 2024-2025 COVID-19 vaccine to maintain their protection against the virus.
| Characteristics | Values |
|---|---|
| COVID-19 cases and hospitalizations among fully vaccinated people | Substantially lower than among unvaccinated people |
| COVID-19 vaccine effectiveness | Reduces cases and hospitalizations |
| COVID-19 vaccine protection | Decreases with time |
| COVID-19 vaccine recommendations | For most adults ages 18 and older |
| COVID-19 vaccine for children | Parents should discuss the benefits with a healthcare provider |
| COVID-19 vaccine boosters | Recommended for people aged 12 years and older |
| COVID-19 vaccine breakthrough cases | Mild to moderate symptoms or asymptomatic |
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What You'll Learn

Vaccines reduce the risk of hospitalisation and death
Vaccines are highly effective in reducing the risk of hospitalisation and death from COVID-19. A study from Brazil found that two-dose vaccines prevented 80-90% of hospitalisations and deaths from reinfection. The CoronaVac vaccine was found to be 81.3% effective against reinfection leading to hospitalisation or death, while the Pfizer vaccine was 89.7% effective, and the AstraZeneca vaccine was 89.9% effective.
Another study found that the BNT162b2 mRNA vaccine reduced the COVID-19-associated mortality risk by 92%. The mRNA-1273 and ChAdOx1 vaccines were also found to be 82% effective against COVID-19-related mortality.
The effectiveness of vaccines in preventing severe illness and death is further supported by a study from Sweden, which found a high level of protection against COVID-19 after two doses of the BNT162b2 vaccine.
Vaccines also reduce the risk of hospitalisation and death for those with prior COVID-19 infections. A study from Stanford Medicine found that vaccines provide additional protection for those who have recovered from COVID-19.
The CDC recommends that most adults aged 18 and older receive a COVID-19 vaccine to protect against severe illness, hospitalisation, and death. While it is possible to get COVID-19 even after vaccination, the illness is likely to be less severe.
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Breakthrough cases are usually mild or asymptomatic
Vaccination is the best way to protect yourself from COVID-19. However, even after vaccination, it is still possible to contract the virus. These are known as "vaccine breakthrough cases". While breakthrough cases are normal, the good news is that they are usually mild or asymptomatic.
Vaccination can make illness less severe in people who experience a vaccine breakthrough infection. According to Dr. Sanghavi, around 25% to 30% of patients with breakthrough infections are completely asymptomatic. About 50% to 60% of patients may have mild symptoms and may not need hospitalization. In comparison, the symptoms of unvaccinated individuals infected with COVID-19 tend to be more severe, with 80% of unvaccinated patients needing hospitalization.
The COVID-19 vaccine helps protect against severe illness, hospitalization, and death. People who have completed at least a primary series are less likely to be hospitalized or die compared to those who are not vaccinated. Additionally, vaccinated individuals experience a faster recovery time, with symptoms lasting only a few days up to two weeks. Furthermore, vaccinated individuals are less likely to experience long-haul COVID-19 symptoms that can last for months after the initial infection.
While it is possible for vaccinated individuals to transmit the virus, the length of time they are contagious is much shorter than if they were unvaccinated. A 2022 study found that people with mild or asymptomatic COVID-19 were no longer contagious after six to nine days of being diagnosed or developing symptoms. Therefore, vaccination not only reduces the severity of the disease but also helps to slow down the spread of the virus.
In summary, while breakthrough cases can occur, they are typically mild or asymptomatic. Vaccination remains crucial in protecting against severe illness and slowing down the spread of COVID-19. It is important to stay up to date with the latest vaccine recommendations to ensure maximum protection against the virus.
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Vaccines are especially important for those vulnerable
While I wasn't able to find information on whether COVID-19 cases are higher or lower after the vaccine, I can confirm that vaccines are especially important for vulnerable people.
Vaccines are a safe and effective way to protect oneself and one's community from preventable diseases. They are particularly crucial for vulnerable individuals who are at a higher risk of contracting and suffering severe complications from certain illnesses. This includes people who are too young, such as infants, or too old to receive certain vaccines, as well as those with weakened immune systems due to underlying health conditions or medical treatments. For example, young babies who are not fully vaccinated, people undergoing chemotherapy for cancer, people with HIV, children on steroids for asthma, pregnant women, and individuals with conditions such as asthma, diabetes, or heart, lung, spleen, or kidney disorders.
Vaccines help to build immunity by training our bodies to create antibodies and memory cells to fight specific infections. This not only protects the individual but also prevents the spread of the disease to others in the community. The more people who are vaccinated, the fewer opportunities a disease has to spread, thus protecting those who are vulnerable and may not be able to receive certain vaccines.
Furthermore, vaccines can reduce the risk of serious complications and long-term consequences associated with certain diseases. For instance, the flu vaccine lowers the chances of hospitalization and death, while also protecting against flu-related pneumonia, heart attacks, and strokes. The hepatitis B vaccine prevents chronic liver damage and cancer caused by HBV infection, and the HPV vaccine protects against cervical cancer and other cancers in both women and men.
It is important to stay up to date with recommended vaccines and their boosters to maintain protection, as immunity can wane over time. By doing so, individuals can protect themselves and play their part in safeguarding vulnerable members of their community.
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Vaccines reduce the risk of long-haul COVID-19
Vaccines are an important tool in the fight against COVID-19, and they play a crucial role in reducing the risk of long-haul COVID-19, also known as "long COVID". Long COVID refers to new or recurring symptoms that persist for more than four weeks after the initial SARS-CoV-2 infection. At the pandemic's onset, about 10% of people who contracted COVID-19 went on to develop long COVID. However, thanks to vaccines, the risk of developing long COVID has decreased significantly.
According to a recent study by Ziyad Al-Aly, MD, and his team, the risk of long COVID among vaccinated individuals (who have received the primary series) is now approximately 3.5%. This finding underscores the significant decline in the likelihood of developing long COVID due to vaccination. The study also revealed that vaccines contributed to about 70% of the decline in long COVID cases, with the numbers being significantly lower in vaccinated cohorts.
Vaccines offer protection against long COVID by reducing the risk of severe acute infections, which are associated with a higher chance of long COVID. Furthermore, vaccines activate the immune system, aiding the body in eliminating the virus more rapidly and reducing the presence of lingering viral particles. This is particularly important because viral persistence is one of the hypothesized drivers of long COVID.
In addition to reducing the risk of developing long COVID, vaccines may also alleviate symptoms for those already suffering from the condition. A study by the Mayo Clinic found that long COVID patients who were vaccinated before contracting the virus were less likely to experience symptoms such as abdominal pain, chest pain, dizziness, and shortness of breath. Akiko Iwasaki, PhD, a professor of immunobiology at Yale School of Medicine, has also reported improvements in symptoms among vaccinated long COVID patients, including the resolution of "brain fog" and gastrointestinal issues.
While vaccines provide significant protection against long COVID, it is important to note that they do not eliminate the risk entirely. Some vaccinated individuals may still develop long COVID, and ongoing research aims to better understand the mechanisms behind this complex condition. Nevertheless, the available data highlights the crucial role of vaccines in mitigating the burden of long COVID and improving the quality of life for those affected.
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Vaccines are updated to protect against current strains
The 2024–2025 COVID-19 vaccines are updated to provide the best protection against the currently circulating strains. The vaccines more closely target the Omicron variant's JN.1 lineage and the KP.2 strain, which is part of the larger FLiRT family of variants. The updated vaccines are expected to provide protection against COVID-19 caused by these currently circulating variants.
The CDC recommends the 2024–2025 COVID-19 vaccine for most adults aged 18 and older, including those who have previously been vaccinated, those who have had COVID-19, and those with long COVID. The vaccine is especially important for those who are pregnant, breastfeeding, trying to get pregnant, or planning to become pregnant in the future. It is also recommended for those aged 65 and older, those at high risk of severe COVID-19, and those who have never been vaccinated.
The FDA considers the updated vaccine to be an annual preventive measure similar to the flu vaccine. The updated mRNA COVID-19 vaccines include Comirnaty and Spikevax, approved for individuals 12 years of age and older, and the Moderna COVID-19 Vaccine and Pfizer-BioNTech. The CDC and FDA emphasize that these updated vaccines meet rigorous safety, effectiveness, and manufacturing quality standards.
While vaccination does not guarantee that one will not get sick, it significantly reduces the risk of severe illness, hospitalization, and death. Vaccination can also help prevent long-haul COVID-19 symptoms and reduce the chance of infecting others. Even in the case of a breakthrough infection, symptoms are typically milder, and the risk of hospitalization and death is lower compared to those who are unvaccinated.
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Frequently asked questions
Yes, some people who are vaccinated will still get COVID-19 if they are exposed to the SARS-CoV-2 virus. These are called "vaccine breakthrough cases". However, vaccination can make illness less severe in people who experience a vaccine breakthrough infection.
As of May 8, 2023, the New York State Department of Health reported 2,823,097 laboratory-confirmed breakthrough cases of COVID-19 among fully-vaccinated people in New York State, which corresponds to 19.1% of the fully-vaccinated population aged 5 and older.
The New York State Department of Health reported 119,202 hospitalizations with COVID-19 among fully-vaccinated people as of May 8, 2023, which corresponds to 0.81% of the fully-vaccinated population aged 5 and older. This is substantially lower than the hospitalization rate among unvaccinated people.
Yes, the CDC recommends that most adults aged 18 and older get the 2024-2025 COVID-19 vaccine, even if they have previously had COVID-19. This is because protection from the COVID-19 vaccine decreases over time, and the vaccines are updated to provide the best protection against currently circulating strains.










































