
Chickenpox, a highly contagious disease caused by the varicella-zoster virus (VZV), can be prevented through vaccination. The varicella vaccine, also known as the chickenpox vaccine, is recommended for children, adolescents, and adults who lack immunity to the virus. Two doses of the vaccine are typically required for protection, and it can be administered alongside other vaccines such as measles, mumps, and rubella (MMR) in a combination known as MMRV. While the vaccine is generally safe, mild side effects such as pain, redness, or swelling at the injection site may occur, and there is a small risk of more severe reactions. Understanding the vaccination history and any potential contraindications is essential before receiving the varicella vaccine.
| Characteristics | Values |
|---|---|
| Name of vaccine | Varicella vaccine |
| Other names | Chickenpox vaccine, MMRV vaccine |
| Number of doses | 2 doses |
| Age of recipient | Children, adolescents, and adults |
| Age of recipient for MMRV | 1 year to 12 years old |
| Age of recipient for 2 doses | Older than 6 but younger than 13 years |
| Interval between doses | 4 to 8 weeks apart |
| Possible side effects | Pain, redness, swelling, fever, febrile seizures, fainting, allergic reaction, rash, shingles |
| People who should not take the vaccine | Pregnant women, people with impaired humoral immunity, HIV infection, serious immune system problems |
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What You'll Learn
- The chickenpox vaccine is called the Varicella vaccine
- Two doses of the vaccine are 90% effective at preventing chickenpox
- The MMRV vaccine is contraindicated for people with impaired humoral immunity
- Possible side effects include pain, redness, swelling, fever, and febrile seizures
- Pregnant women should not get the chickenpox vaccine until after giving birth

The chickenpox vaccine is called the Varicella vaccine
The Varicella vaccine is recommended for individuals who do not have evidence of immunity to chickenpox, including those who have neither had chickenpox nor received the vaccine. Two doses of the vaccine are recommended for children, adolescents, and adults who fall into this category. The CDC specifically recommends two doses for preschool-age children (12 months through 3 years), while older children, adolescents, and adults are advised to receive two doses of the vaccine 4 to 8 weeks apart.
The Varicella vaccine is highly effective in preventing chickenpox. Two doses of the vaccine are about 90% effective at preventing the disease. The vaccine not only prevents severe illness in almost all vaccinated individuals but also effectively prevents mild illness. In the rare event that a vaccinated person contracts chickenpox, they typically experience a mild case.
In addition to the standalone Varicella vaccine, there is also a combination vaccine called MMRV, which includes measles, mumps, rubella, and varicella. MMRV is only licensed for children aged one to twelve years old. It is important to note that MMRV is contraindicated for people with impaired humoral immunity and HIV infection. For those with contraindications to the MMRV vaccine, varicella-zoster immune globulin may be administered after exposure to chickenpox or herpes zoster.
While the Varicella vaccine is generally safe, mild side effects such as pain, redness, or swelling at the injection site may occur. Some individuals may also experience a fever. More rarely, a mild chickenpox rash can develop up to a month after vaccination and should clear up without treatment. However, during this time, the virus can spread to those without immunity to chickenpox. Therefore, anyone experiencing a rash after vaccination should avoid contact with infants and immunocompromised individuals until the rash resolves.
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Two doses of the vaccine are 90% effective at preventing chickenpox
Chickenpox, also known as Varicella, is a highly contagious disease caused by the varicella-zoster virus (VZV). While chickenpox is usually mild, it can be serious in infants under 12 months of age, adolescents, adults, pregnant people, and those with weakened immune systems. In rare cases, some people get so sick that they require hospitalization and may even die from chickenpox.
The varicella vaccine is highly effective in preventing chickenpox infections and has been a part of the U.S. Chickenpox Vaccination Program. Two doses of the vaccine are 90% effective at preventing chickenpox. The CDC recommends two doses of the vaccine for children, adolescents, and adults who do not have evidence of immunity. This includes those who have neither had chickenpox nor received the vaccine before.
The timing between the two doses depends on the recipient's age. For kids between the ages of 6 and 12, the recommended interval is three months. For older kids, adolescents, and adults aged 13 and above, the doses should be given closer together, with an interval of one to two months. It's worth noting that the MMRV vaccine, which combines the measles, mumps, rubella, and varicella vaccines, is only licensed for children between the ages of 1 and 12. For those 13 and older, the single-antigen varicella vaccine is recommended.
While the varicella vaccine is highly effective, it's important to be aware of possible side effects. Mild effects may include pain, redness, or swelling at the injection site, and some individuals may experience a fever. In rare cases, more serious reactions can occur, such as febrile seizures, pneumonia, infection of the brain or spinal cord covering, and, in individuals with serious immune system problems, a potentially life-threatening infection. Additionally, there is a small risk of developing shingles (herpes zoster) years after receiving the vaccine, but this is much less common than getting shingles after having had chickenpox.
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The MMRV vaccine is contraindicated for people with impaired humoral immunity
The chickenpox vaccine is called the varicella vaccine. It is also known as MMRV, which stands for measles, mumps, rubella, and varicella. The MMRV vaccine is contraindicated for people with impaired humoral immunity, which includes those with hypogammaglobulinemia, dysgammaglobulinemia, or HIV infection.
Humoral immunity refers to the antibody response to an antigen, which is critical for immunity against viral infections. Live attenuated vaccines, such as MMRV, work by eliciting a humoral immune response. However, in individuals with impaired humoral immunity, the effectiveness of the vaccine may be limited.
Hypogammaglobulinemia and dysgammaglobulinemia are conditions that affect the body's ability to produce antibodies, which are essential for fighting infections. Individuals with these conditions may have a reduced ability to respond to vaccines and develop immunity. HIV infection can also lead to impaired humoral immunity, as it attacks the immune system, specifically targeting antibody-producing cells.
It is important to note that the contraindication for the MMRV vaccine in individuals with impaired humoral immunity is a precaution to ensure their safety. Alternative options, such as the single-antigen varicella vaccine, may be recommended for these individuals to protect them from chickenpox while taking their specific health considerations into account.
While the MMRV vaccine is a convenient option for protecting against measles, mumps, rubella, and chickenpox, it may not be suitable for everyone. For individuals with impaired humoral immunity, consulting with healthcare professionals is crucial to determine the most appropriate vaccination strategy, considering their unique health needs and risks.
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Possible side effects include pain, redness, swelling, fever, and febrile seizures
The chickenpox vaccine is called the varicella vaccine. It is sometimes given in combination with the vaccine for measles, mumps, and rubella (MMR) in a single shot called MMRV.
Possible Side Effects
Possible mild side effects of the varicella vaccine include pain, redness, or swelling where the shot was given. Some recipients may also experience fever, and there is a very small risk of febrile seizures, especially after vaccination with MMRV. These side effects are not unique to the varicella vaccine, as pain, redness, swelling, and fever can occur with any vaccine.
Febrile seizures are convulsions that can occur when a child has a high fever. They are the most common type of seizure in children and usually happen between the ages of 6 months and 5 years. While febrile seizures can be frightening, they usually stop on their own and do not cause any long-term problems. However, it is important to seek medical attention if a child experiences a seizure, as it could be a sign of a more serious condition.
In addition to the mild side effects mentioned above, there is also a small risk of fainting after receiving the varicella vaccine, as some people may feel dizzy or experience changes in their vision or ringing in their ears. Although rare, there is also a very small chance of an allergic reaction, which could be severe. Symptoms of a severe allergic reaction include hives, swelling of the face and throat, difficulty breathing, a fast heartbeat, dizziness, or weakness. If any of these symptoms occur, it is important to seek immediate medical attention.
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Pregnant women should not get the chickenpox vaccine until after giving birth
Chickenpox is a highly contagious disease caused by the varicella-zoster virus. While chickenpox is usually not dangerous in children, some people are at higher risk of complications from the disease, including pregnant women and newborns.
The varicella vaccine is an injection that contains a live but weakened varicella virus. It is given in two doses and causes the body to make antibodies to the virus, protecting the recipient from infection in the future. The vaccine is not approved for everyone, however. The CDC recommends that all adults be assessed for immunity to chickenpox, and the American Academy of Pediatrics and the Advisory Committee on Immunization Practices of the CDC do not recommend getting live virus vaccines during pregnancy due to theoretical concerns.
Pregnant women who get chickenpox in their first or early second trimester can pass the virus to their babies, which can cause birth defects. Additionally, if a woman develops chickenpox shortly before going into labor, the newborn is at risk of being born with chickenpox. While such complications are rare, it is important to take steps to prevent them. If a pregnant woman is not immune to chickenpox, she should get the vaccine after giving birth to protect herself, her baby, and future pregnancies. The vaccine is safe for breastfeeding women and their babies.
If a pregnant woman is not immune to chickenpox and contracts the disease, there are treatments available. Antivirals are a type of medicine that can treat infections caused by viruses, and they are safe to use during pregnancy. They work best when given within 24 hours of the chickenpox rash appearing. If a woman develops signs or symptoms of pneumonia, she may be treated with acyclovir through an IV. Additionally, if a baby's mother has chickenpox during pregnancy, the newborn may be treated with medicine that contains chickenpox antibodies right after birth. This can help prevent chickenpox in the baby or make the disease less dangerous.
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Frequently asked questions
The chickenpox vaccine is called the varicella vaccine.
MMRV stands for measles, mumps, rubella, and varicella (chickenpox). It is a combination vaccine that protects against all four diseases.
The CDC recommends that children, adolescents, and adults who do not have evidence of immunity to chickenpox receive the vaccine.
Mild side effects may include pain, redness, or swelling at the injection site, as well as fever. More serious reactions are rare but may include pneumonia, infection of the brain and/or spinal cord covering, or seizures.




