
The Pfizer vaccine's effectiveness against the Delta variant has been the subject of much debate and conflicting findings. While some studies, including one from Israel's health ministry, suggest that the vaccine is significantly less effective against the Delta variant than previous strains, other studies, such as those published in The Lancet journal, indicate strong protection against the variant. The discrepancy in results may be due to various factors, including the methodology of the studies, the high transmissibility of the variant, and the potential waning of immunity over time. Overall, while the Pfizer vaccine may offer slightly lower protection against the Delta variant compared to other strains, it is still considered highly effective in preventing serious illness and hospitalization caused by this variant, especially after two doses.
| Characteristics | Values |
|---|---|
| Protection against the Delta variant | 79% two weeks after the second dose |
| Protection against the Alpha variant | 92% two weeks after the second dose |
| Effectiveness in preventing infection | 64% |
| Effectiveness in preventing symptomatic illness | 64% |
| Effectiveness in preventing serious illness and hospitalization | 93% after two doses |
| Booster shot effectiveness | Antibody levels in 18-55 year olds were five times greater than after the second dose |
| Booster shot effectiveness | Antibody levels in 65-85 year olds were 11 times greater than after the second dose |
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What You'll Learn
- The Pfizer vaccine is 92% effective against the Alpha variant
- The vaccine is 79% effective against Delta two weeks after the second dose
- The vaccine is 64% effective at preventing symptomatic Covid-19 caused by the Delta variant
- The Delta variant doubles the risk of hospitalisation compared to the Alpha variant
- The Pfizer vaccine is 93% effective at preventing serious illness and hospitalisation caused by the Delta variant

The Pfizer vaccine is 92% effective against the Alpha variant
The Pfizer vaccine is highly effective in preventing serious illness and hospitalisation caused by the Alpha variant of the coronavirus. According to a study published in The Lancet journal, the Pfizer vaccine offered 92% protection against the Alpha variant and 79% protection against the Delta variant two weeks after the second dose. The study, conducted by researchers at Public Health Scotland and the University of Edinburgh, UK, analysed 19,543 confirmed SARS-CoV-2 infections, of whom 377 were admitted to hospital for COVID-19 in Scotland.
The high efficacy of the Pfizer vaccine against the Alpha variant is encouraging, as it demonstrates the vaccine's ability to provide strong protection against this particular strain of the virus. The Alpha variant, first found in the UK, is known to double the risk of hospitalisation compared to other variants, such as the Delta variant, which was first identified in India.
While the Pfizer vaccine offers slightly lower protection against the Delta variant compared to the Alpha variant, it still provides good protection against this strain. The same study found that the risk of COVID-19 hospital admission was approximately doubled in those with the Delta variant compared to the Alpha variant, especially in individuals with five or more relevant comorbidities. However, the Pfizer vaccine was found to be more effective than the Oxford-AstraZeneca vaccine in offering protection against the Delta variant.
It is important to note that the effectiveness of vaccines, including Pfizer, may wane over time, and the emergence of new variants, such as Delta, has led to discussions about the potential need for booster shots. Some countries, like Israel, have approved booster shots for immunocompromised individuals, while others, like the US, have stated that fully vaccinated individuals do not need a booster shot at the moment.
Overall, the Pfizer vaccine's 92% effectiveness against the Alpha variant is a testament to its ability to provide strong protection against this specific strain of the coronavirus, contributing to its overall success in reducing the risk of hospitalisation and severe illness associated with COVID-19.
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The vaccine is 79% effective against Delta two weeks after the second dose
The Pfizer vaccine is 79% effective against the Delta variant two weeks after the second dose. This information comes from a study published in The Lancet journal by researchers at Public Health Scotland and the University of Edinburgh, UK. The study covered the period from April 1 to June 6, 2021, and analysed 19,543 confirmed SARS-CoV-2 infections, of which 377 were hospitalised for COVID-19 in Scotland. The researchers also found that two doses of the vaccine provide much better protection against the Delta variant compared to a single dose.
The high effectiveness of the Pfizer vaccine against the Delta variant is further reinforced by an Israeli study, which found that the vaccine is 93% effective at preventing serious illness and hospitalisation caused by the Delta variant after two doses. This is only slightly lower than its effectiveness against other variants.
However, it is important to note that the Israeli study has been criticised for not considering potential differences between vaccinated and unvaccinated individuals, such as their willingness to get tested or adhere to public health guidelines.
Despite the criticism of the Israeli study, other studies have also found that the Pfizer vaccine provides strong protection against the Delta variant. These studies indicate a higher degree of protection against infection and mild illness, ranging between 80% and 90%.
While the Pfizer vaccine is highly effective against the Delta variant, there has been some discussion about the potential need for booster shots to address waning immunity and provide additional protection against the variant. Pfizer has cited evidence of declining immunity over time, and their data suggests that a third shot can significantly increase antibody levels against the Delta variant.
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The vaccine is 64% effective at preventing symptomatic Covid-19 caused by the Delta variant
According to preliminary findings from a study by Israel's health ministry, the Pfizer-BioNTech vaccine is 64% effective at preventing symptomatic Covid-19 caused by the Delta variant. This is based on data showing that the vaccine is 64% effective at preventing infection with the Delta variant. This conflicts with other studies, which indicate a higher degree of protection against infection and mild illness, between 80% and 90%.
The discrepancy in the data may be due to the maturity of Israel's vaccination program and the high prevalence of the Delta variant in the country. Israel's study also did not consider the potential differences between vaccinated and unvaccinated individuals, who may differ in their willingness to get tested or adhere to public health guidelines.
Despite the conflicting data, the Pfizer vaccine is still highly effective at preventing serious illness and hospitalization caused by the Delta variant. An Israeli study found that the vaccine is 93% effective at preventing serious illness and hospitalization after two doses, only slightly lower than its effectiveness against other variants.
The importance of the second dose in fending off the Delta variant has been reinforced by studies, which found that two doses of the vaccine provide much better protection against the Delta variant compared to a single dose.
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The Delta variant doubles the risk of hospitalisation compared to the Alpha variant
The Delta variant of the COVID-19 virus was first identified in India in late 2020. It soon spread worldwide, becoming the predominant version of the coronavirus until Omicron took its place in mid-December 2021. The Delta variant is estimated to have caused more than twice as many infections as previous variants. It was found to be up to 50% more transmissible than the Alpha variant, which was first identified in the UK.
According to Rebecca Wurtz, an infectious disease expert at the University of Minnesota School of Public Health, the Delta variant's increased contagiousness is due to it producing more viral particles. It also works more quickly, meaning it can gain a foothold in the body before the immune system has a chance to respond. This explains why vaccines can be less effective against infection with the Delta variant.
Multiple studies have shown that full vaccination prevents infection with symptoms and hospitalisation for both the Alpha and Delta variants. The Pfizer-BioNTech vaccine has been found to offer better protection against the Delta variant compared to the Oxford-AstraZeneca vaccine. A full course of the Pfizer vaccine is 64% effective at preventing infection and symptomatic illness caused by the Delta variant, according to a study by Israel's health ministry. Another Israeli study found that the Pfizer vaccine is 93% effective at preventing serious illness and hospitalisation caused by the Delta variant after two doses.
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The Pfizer vaccine is 93% effective at preventing serious illness and hospitalisation caused by the Delta variant
The Pfizer vaccine is highly effective at preventing serious illness and hospitalisation caused by the Delta variant. According to an Israeli study, the Pfizer vaccine is 93% effective at preventing hospitalisation caused by the Delta variant after two doses. This is only slightly lower than its effectiveness against other variants. Dr. David Strain commented that this means the vaccine is "doing its job really well", given that preventing hospitalisation is the key purpose of a vaccine.
However, the same Israeli study also found that the Pfizer vaccine is less effective at preventing infection and symptomatic illness with the Delta variant compared to previous strains. The study's preliminary findings showed that two doses of the Pfizer vaccine are 64% effective at preventing infection and symptomatic Covid-19 caused by the Delta variant. This is significantly lower than the level of protection offered against other variants.
These findings conflict with other studies, which indicate a much higher degree of protection against infection and mild illness (between 80% and 90%). The discrepancy may be due to flaws in the Israeli study, as pointed out by Harvard Medical School Professor Rebecca Weintraub. Another potential explanation is that Israel has a high proportion of fully vaccinated people and a mature vaccination program, along with a high prevalence of the Delta variant.
Despite the lower effectiveness against infection, the Pfizer vaccine still provides good protection against the Delta variant. Researchers at Public Health Scotland and the University of Edinburgh found that the Pfizer vaccine offered 79% protection against the Delta variant two weeks after the second dose. This is higher than the protection offered by the AstraZeneca vaccine, which provided 60% protection against the Delta variant.
Overall, while the Pfizer vaccine may be slightly less effective against the Delta variant than other strains, it still offers strong protection against serious illness and hospitalisation caused by this variant.
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Frequently asked questions
According to a study from Israel's health ministry, the Pfizer vaccine is 64% effective at preventing infection and symptomatic illness caused by the Delta variant. However, other studies indicate that the vaccine offers a much higher degree of protection, ranging from 79% to 90%.
The Pfizer vaccine is slightly less effective against the Delta variant compared to other variants. However, it is still highly effective at preventing serious illness and hospitalization caused by the Delta variant, with a 93% effectiveness rate after two doses, according to an Israeli study.
The need for booster shots to boost waning immunity and provide additional protection against the Delta variant is a contentious topic. While Pfizer has cited evidence of waning immunity and is pushing for booster shots, U.S. regulators and the World Health Organization head have stated that fully vaccinated individuals do not need a booster shot at this time.
According to a study published in The Lancet journal, the Pfizer vaccine offered better protection against the Delta variant compared to the AstraZeneca vaccine. The Pfizer vaccine provided 79% protection against the Delta variant, while the AstraZeneca vaccine provided 60% protection.




















