Chloe Ramirez
There is much debate surrounding the topic of whether or not the mRNA vaccine stays in your blood. Some sources claim that the vaccine can cause blood clots and lead to serious health issues, while others argue that these claims are unfounded and that the vaccine is safe. A study by Castruita et al. found fragments of COVID-19 vaccine mRNA in blood samples up to 28 days post-vaccination, raising questions about the presence of the vaccine in the bloodstream. However, it is important to consider the potential biases and motivations of sources when evaluating the validity of their claims.
| Characteristics | Values |
|---|---|
| Does the mRNA vaccine stay in your blood? | Fragments of COVID-19 vaccine mRNA were found in blood samples of vaccinated patients up to 28 days post-vaccination. However, another study found that only 9.3% of blood samples contained mRNA nanoparticles from COVID-19 vaccines. |
| Adverse effects | There are concerns about the adverse effects of the vaccine, including the formation of multiple tiny blood clots, pulmonary artery hypertension, and myocarditis. |
| Safety concerns | Some sources claim that the vaccine is unsafe, especially for children, due to the risk of blood clot formation and other potential long-term health complications. |
| Efficacy concerns | Some sources question the efficacy of the vaccine, suggesting that it may not provide adequate protection against COVID-19. |
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What You'll Learn
A study found COVID-19 vaccine mRNA in blood samples
While studying hepatitis, Castruita et al. decided to test the blood samples of their patients who had received COVID-19 mRNA vaccines. They distinguished between vaccinated and unvaccinated persons to have a control group. They also distinguished between vaccine mRNA and viral RNA of Sars-Cov-2. The study surprisingly found fragments of COVID-19 vaccine mRNA up to 28 days post-vaccination in blood from chronic HCV patients vaccinated with mRNA vaccines from both Pfizer-BioNTech and Moderna.
Of the 108 patient samples, 10 samples (9.3%) had partial or up to full sequences of the vaccine mRNA sequence, identified from one to 28 days post-vaccination. There was ~100% identity between the detected mRNA nucleotide sequences found in plasma and the specific mRNA vaccine given. The 10 samples had a median of 5.5 million raw read pairs available. Breadth and depth of coverage of the vaccine mRNA sequences ranged from completeness and >20 000, respectively, to short fragments with a depth of coverage of 100. None of the negative or the HCV-positive controls had SARS-CoV-2 matching reads.
The study debunked the myth of "vaccine staying at the injection site" and another myth of "vaccinated blood does not contain vaccine mRNA." However, it also showed that 98 samples out of 108 did not have vaccine mRNA detected. This means that while most people who received COVID-19 vaccines did not have their blood contaminated with the vaccine, a sizable minority did. As time passes after the last dose, the amount of contamination likely declines in quantity and frequency of occurrence.
Another study by researcher Sandeep Chakraborty identified the presence of unexpected DNA sequences in the blood of individuals vaccinated with mRNA COVID-19 vaccines. These findings have been independently validated by Kevin McKernan, former director of the Human Genome Project, and Phillip Buckhaults, a Professor from the University of South Carolina. Alongside the spike protein sequence, there were also gene fragments encoding for "SV40" and "Kanamycin" - genetic sequences unique to the plasmid DNA used in mRNA vaccine production. Professor Nikolai Petrovsky emphasised that the high levels of plasmid DNA fragments detected in the blood samples implied serious issues with manufacturing quality control of the mRNA vaccines.
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Blood clot formation linked to mRNA vaccines
There is a theory that the spike protein in mRNA COVID-19 vaccines can lead to the development of multiple tiny blood clots. This is because the spike protein becomes part of the cell wall of the vascular endothelium, which lines the blood vessels. As a result, the usually smooth surface of these cells becomes uneven, with "spiky bits sticking out". Consequently, blood clots form as platelets circulate and detect the damaged blood vessels, attempting to block the damage. This theory has been propagated by Charles Hoffe, a family physician from Lytton, British Columbia, who claimed that 62% of his patients showed evidence of clotting after receiving a COVID-19 vaccine. Hoffe further asserted that the long-term outlook is grim, as successive shots will lead to more damaged capillaries and potentially irreversible conditions such as pulmonary artery hypertension.
However, it is important to note that the specific condition of Thrombosis with Thrombocytopenia Syndrome (TTS), also known as Vaccine-Induced Immune Thrombotic Thrombocytopenia (VITT), has primarily been associated with certain viral vector vaccines. TTS involves both thrombosis (blood clot formation) and thrombocytopenia, characterised by abnormally low levels of platelets in the blood. While cases of TTS/VITT have been linked to the Johnson & Johnson and AstraZeneca COVID-19 vaccines, this syndrome has not been identified as a risk following vaccination with mRNA vaccines from Pfizer-BioNTech and Moderna. In fact, data indicates that TTS occurs at an extremely low rate of approximately 3.8 cases per million doses of the Johnson & Johnson vaccine. Furthermore, studies have shown that COVID-19 vaccines, including mRNA-based vaccines, are effective in reducing thrombotic events and disease severity in individuals infected with SARS-CoV-2.
While the link between blood clot formation and mRNA vaccines remains controversial, with some studies refuting this connection, it is important to be aware of the potential risks and symptoms associated with any medical treatment. Symptoms of blood clots can include severe headaches, blurred vision, shortness of breath, chest pain, swelling in the legs, persistent abdominal pain, and tiny blood spots under the skin, known as petechiae. These symptoms typically appear within 4 to 42 days after vaccination, and if they occur, immediate medical attention is advised.
Additionally, it is worth noting that a study by Castruita et al. found fragments of COVID-19 vaccine mRNA in the blood of vaccinated individuals up to 28 days post-vaccination. However, this study also showed that most people who received COVID-19 vaccines did not have their blood contaminated with the vaccine, as 98 out of 108 samples did not contain vaccine mRNA.
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Concerns about accepting vaccinated blood transfusions
While some people have expressed concerns about accepting blood transfusions from vaccinated individuals, it is important to examine the underlying reasons for these concerns and assess their validity.
One of the primary concerns arises from the belief that COVID-19 mRNA vaccines can contaminate the blood of those who receive them. This belief is based on the results of a study by Castruita et al., which found fragments of COVID-19 vaccine mRNA in the blood of vaccinated individuals up to 28 days post-vaccination. However, it is important to interpret these findings in context. The study in question tested blood samples from patients vaccinated with mRNA vaccines while studying a separate topic related to hepatitis. Out of 108 patient samples, only 10 samples (9.3%) contained partial or full sequences of the vaccine mRNA sequence. This means that while a small minority of vaccinated individuals may have vaccine mRNA in their blood, the majority do not.
The presence of vaccine mRNA in the blood has raised concerns about the potential risks associated with receiving a blood transfusion from a vaccinated donor. Some people worry that the vaccine mRNA could be transmitted through the transfusion and potentially trigger adverse effects in the recipient. However, it is important to note that the presence of vaccine mRNA in the blood does not necessarily indicate contamination or pose a safety risk. The human body has mechanisms to break down and eliminate foreign substances, including mRNA, over time. Additionally, blood banks have rigorous testing and screening procedures in place to ensure the safety and compatibility of donated blood.
Despite these reassurances, some individuals remain hesitant to receive blood from vaccinated donors. This hesitancy has led to the emergence of specialised services, such as SafeBlood, that match unvaccinated blood donors with recipients who specifically request unvaccinated blood. This development highlights the diverse preferences and concerns within the broader community.
While the concerns about accepting vaccinated blood transfusions are understandable, it is essential to consider the weight of scientific evidence and the established safety protocols in blood donation processes. The presence of vaccine mRNA in a small minority of vaccinated individuals does not necessarily indicate a safety risk for blood transfusion recipients. Rigorous testing, screening, and compatibility checks are routinely performed to ensure the safety of donated blood. As with any medical decision, it is advisable to consult with healthcare professionals and follow the guidance of reputable health organisations.
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The spike protein in the vaccine can lead to blood clots
There have been concerns about the potential side effects of the COVID-19 vaccine, particularly regarding the formation of blood clots. The spike protein in the vaccine is thought to be the key causative agent of damage to vascular endothelial cells. This is because the spike protein becomes part of the cell wall of the vascular endothelium, causing "spiky bits [to stick] out", disrupting the smooth flow of blood. This can lead to the development of multiple tiny blood clots, which can have serious health consequences, including pulmonary artery hypertension and an increased risk of myocarditis.
Research has shown that the spike protein alone is toxic. Studies dating back to 2015 indicated that even a small amount of spike protein could cause lung disease in hamsters. The spike protein in the COVID-19 vaccine has been modified in ways that may make it more dangerous, including the addition of a furin cleavage site, which increases toxicity, and the removal of an enzyme that typically protects the body against natural coronaviruses. These modifications can make the spike protein more prone to causing blood clotting by encouraging platelets and red blood cells to stick together.
The presence of the spike protein in the bloodstream can also provoke an immune response, leading to autoimmune-like conditions. When cells in blood vessel walls produce the spike protein, the immune system may perceive them as foreign and attack them, further contributing to inflammation and damage to vascular endothelial cells.
The risk of blood clot formation is a significant concern, as it can lead to serious health issues and even death. Some researchers have expressed concern about administering the COVID-19 vaccine to children due to their limited ability to defend against potential adverse effects. However, it is important to note that the presence of mRNA from the vaccine in the blood has been disputed, with some studies finding no evidence of it, while others have detected fragments of mRNA up to 28 days post-vaccination.
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Heart damage and failure linked to mRNA vaccines
There is evidence that the Pfizer/BioNTech and Moderna mRNA vaccines may rarely cause inflammation of the heart muscle (myocarditis) or of the surrounding lining (pericarditis), particularly in male adolescents and young adults. Myocarditis and pericarditis have been identified as rare side effects of the mRNA COVID-19 vaccines, especially in young males after a second dose. However, the benefits of COVID-19 vaccination outweigh the risks for males and females in all age groups.
The FDA has approved updated warning labels for the Pfizer and Moderna vaccines, highlighting the risk of myocarditis and pericarditis. The warning conveys that the observed risk of these conditions following vaccination is highest in males 12 through 24 years of age. The FDA closely monitors the safety of all vaccines, including mRNA COVID-19 vaccines, and remains committed to informing the public of any new information.
Several studies have found that COVID-19 infection increases the risk of heart complications more significantly than mRNA vaccines. A large study published in Nature Medicine found that COVID-19 increased the risk for several heart disorders, including heart attacks, arrhythmias, strokes, cardiac arrests, and myocarditis. The Centers for Disease Control and Prevention (CDC) has also stated that the risk of cardiac complications is higher after SARS-CoV-2 infection than after receiving an mRNA vaccine.
There have been concerns about the presence of mRNA in the blood of vaccinated individuals. A study by Castruita et al. found fragments of COVID-19 vaccine mRNA in the blood of chronic HCV patients up to 28 days post-vaccination. However, another study showed that out of 108 blood samples, only 9.3% contained mRNA nanoparticles from COVID-19 vaccines. It is important to note that the presence of mRNA in the blood does not necessarily indicate contamination or cause for concern.
While myocarditis cases associated with mRNA vaccines are rare, they can have serious consequences in rare instances. Myocarditis can damage the heart and make it difficult for it to pump blood, potentially leading to heart failure, heart attack, and stroke. However, it is important to note that most cases of myocarditis are mild, and acute myocarditis tends to resolve quickly after vaccination. Health authorities emphasize that fatal outcomes from vaccine-related myocarditis are extremely rare, and there have been no reported deaths directly tied to COVID vaccine-triggered myocarditis in the US.
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