
Hepatitis A and Hepatitis B are two of the most common vaccine-preventable diseases in travellers. Hepatitis A is spread by consuming contaminated food or water or through close contact with an infected person, while Hepatitis B is transmitted through contact with infected body fluids. Both diseases are serious liver infections that can be fatal. Vaccines for Hepatitis A and Hepatitis B are available separately or as a combination vaccine, Twinrix, which is administered as a series of three doses over six months or four doses over one month with a booster after one year. The combination vaccine is recommended for individuals aged 18 and above who are at high risk of infection, including those with chronic liver disease, people with hepatitis C, and those who are sexually active. While the vaccine is generally safe and well-tolerated, some mild side effects may occur, such as redness and pain at the injection site.
| Characteristics | Values |
|---|---|
| What is Hepatitis A? | A serious, and sometimes fatal, liver disease caused by the Hepatitis A virus (HAV). |
| How is Hepatitis A spread? | Hepatitis A is spread by consuming contaminated food or water, or through close contact with an infected person. |
| What is Hepatitis B? | A serious liver disease caused by the Hepatitis B virus (HBV). |
| How is Hepatitis B spread? | Hepatitis B is spread by contact with infected body fluids, such as blood, saliva, semen, or vaginal fluids, or through the use of contaminated objects like toothbrushes or razors. |
| Who should get the Hepatitis A and B combination vaccine? | The vaccine is recommended for adults (18+) who are at increased risk of infection, including those with certain jobs or behaviours, those with chronic liver disease, people with hepatitis C, and travellers to certain areas. |
| How is the vaccine administered? | The vaccine is given by injection into the muscle, typically in 3 doses over 6 months, or 4 doses over 1 month with a booster after 12 months. |
| Are there any side effects? | Common side effects include redness and pain at the injection site, fatigue, headaches, and mild flu-like symptoms. Severe side effects are rare but may include allergic reactions and seizures. |
| Are there any precautions or contraindications? | The vaccine should be avoided by those with severe allergies to any of its components, and those with moderate to severe illnesses should wait until they recover. Pregnant women should consult their doctor before receiving the vaccine. |
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What You'll Learn
- Hepatitis A and B are two of the most common vaccine-preventable diseases in travellers
- The hepatitis A and B vaccine is recommended for those at risk of infection through their job or behaviours
- The vaccine is also recommended for those at risk of infection through travel to certain areas
- The hepatitis A and B vaccine is administered via injection into a muscle
- The vaccine is safe and protective, with mild side effects including redness and pain at the injection site

Hepatitis A and B are two of the most common vaccine-preventable diseases in travellers
Hepatitis A and hepatitis B are serious liver diseases caused by the hepatitis A and B viruses. Both viruses are endemic in much of the developing world, and there is considerable overlap of high-endemicity areas for both diseases. This makes travellers particularly vulnerable to contracting hepatitis A and B.
Hepatitis A is transmitted through direct person-to-person contact or the ingestion of contaminated food or water. The risk of transmission is highest in rural areas with poor sanitation, but it can also be contracted in standard tourist accommodations. It is recommended that travellers receive the hepatitis A vaccine, which is safe and highly effective, even for people with compromised immune systems.
Hepatitis B is spread by contact with bodily fluids, such as blood, saliva, semen, or vaginal fluids, as well as by needle sticks or sharing needles. Travellers can be at risk of contracting hepatitis B if they engage in activities such as getting a manicure, pedicure, tattoo, piercing, or acupuncture with improperly sterilized tools.
A combination vaccine for hepatitis A and B is available for individuals aged 18 and older, offering protection against both viruses. This vaccine is recommended for travellers at risk of infection due to their destination or behaviours.
It is important to consult a doctor to determine the appropriate vaccination schedule and to ensure the vaccine is working properly through blood tests.
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The hepatitis A and B vaccine is recommended for those at risk of infection through their job or behaviours
Hepatitis A and hepatitis B are two serious liver diseases caused by the hepatitis A and B viruses. Hepatitis A is spread most often through infected food or water, whereas hepatitis B is spread by contact with bodily fluids such as blood, saliva, semen, or vaginal fluids. Hepatitis A and B are two of the most common vaccine-preventable diseases in travellers.
The hepatitis A and B vaccine is recommended for all persons 18 years of age or older who are at risk of infection from their jobs or behaviours. This includes military personnel, laboratory workers who handle the hepatitis A and B viruses, police, those who give first aid or medical help, and workers who come into contact with stool or sewage. Other at-risk groups include people who work in child daycare centres and correctional facilities, residents of drug and alcohol treatment centres, and patients and staff in hemodialysis units.
People who engage in certain behaviours are also recommended to get the hepatitis A and B vaccine. This includes men who have sex with men, people who use illegal injection drugs, and people who are not in long-term, mutually monogamous relationships. Additionally, people with certain medical conditions are at increased risk of infection and may benefit from the vaccine. This includes people with hemophilia, chronic liver disease, end-stage renal disease, and diabetes.
It is important to note that the hepatitis A and B vaccine may not protect everyone who receives it, and it will not treat symptoms of hepatitis A or B infection if the person is already infected. Completing the vaccine dosing schedule is important for achieving the best possible protection against infection. Additionally, the vaccine may cause some unwanted side effects, such as soreness, swelling, and redness at the injection site.
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The vaccine is also recommended for those at risk of infection through travel to certain areas
Hepatitis A is a serious, and potentially fatal, liver disease caused by the hepatitis A virus (HAV). It is spread most often through infected food or water, and close contact with infected persons. Hepatitis B is also a serious liver disease, caused by the hepatitis B virus (HBV) and spread by contact with infected bodily fluids. Both viruses are endemic in much of the developing world, and even travellers to 5-star resorts in certain areas are at risk of infection.
Hepatitis A and hepatitis B are two of the most common vaccine-preventable diseases in travellers. Vaccination is the best way to prevent infection, and there are separate vaccines for hepatitis A and hepatitis B, as well as a combination vaccine that protects against both viruses. The combination vaccine is recommended for all persons 18 years of age or older who are at risk of infection through travel to certain areas. These areas include Central and South America, Eastern and Southern Europe, South and Southeast Asia (except Japan), the Caribbean, and the Middle East.
If you are planning to travel internationally, it is important to talk to your doctor about getting vaccinated against hepatitis A and/or hepatitis B as early as possible. Even late vaccination can have some impact, and your doctor may recommend immune globulin to protect you for up to 2 months if you cannot get the hepatitis A vaccine or are at a higher risk for the disease. For full protection, you will need two or three shots, depending on the type of vaccine.
Infants aged 6-11 months travelling outside the United States when protection against hepatitis A is recommended should be administered the single-antigen hepatitis A vaccine. However, hepatitis A vaccine doses administered before 12 months of age could result in a suboptimal immune response, and the 2-dose hepatitis A vaccine series should be initiated at 12 months according to the routine immunization schedule.
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The hepatitis A and B vaccine is administered via injection into a muscle
Hepatitis A and hepatitis B are two of the most common vaccine-preventable diseases in travellers. Hepatitis A is a serious, and sometimes fatal, disease of the liver that is spread by infected food or water, or close contact with an infected person. Hepatitis B is also a serious liver disease caused by the hepatitis B virus (HBV) and is spread by contact with bodily fluids, including blood, saliva, semen, and vaginal fluids. Both hepatitis A and hepatitis B vaccines are available separately, but there is also a combination vaccine that protects against both viruses.
The hepatitis A and B combination vaccine is administered via injection into a muscle and is used in areas where hepatitis A and B are endemic, for travellers, people with hepatitis C or chronic liver disease, and those at high risk of sexually transmitted diseases. It is given as a standard series of three doses at 0, 1, and 6 months, or as an accelerated series of four doses at 0, 7, 21-30 days, with a booster at 12 months for travellers. The combination vaccine is recommended for all persons 18 years of age or older who are at risk of infection from their jobs, certain behaviours, or travel to certain parts of the world.
This vaccine works by causing the body to produce its own protection (antibodies) against the disease. It is generally well-tolerated, and common side effects are mild, including redness and pain at the injection site, where a small lump may appear. However, severe side effects, although rare, may include serious allergic reactions and seizures. It is important to consult a doctor before receiving the vaccine, as there are certain medical conditions and allergies that may prevent someone from getting the vaccine.
To get the best possible protection against hepatitis A and hepatitis B infection, it is important to complete the vaccine dosing schedule. A booster dose is typically given at least 12 months after the first dose for patients receiving four doses. It is also important to note that this vaccine will not treat symptoms of hepatitis A or hepatitis B infection if a person already has the disease.
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The vaccine is safe and protective, with mild side effects including redness and pain at the injection site
Hepatitis A and Hepatitis B are two of the most common vaccine-preventable diseases in travellers. Hepatitis A is spread most often through infected food or water, whereas Hepatitis B is spread by contact with bodily fluids. Both viruses are endemic in much of the developing world, including popular travel destinations such as the Caribbean.
There are separate vaccines for hepatitis A and hepatitis B, as well as a combination vaccine that protects against both viruses. The hepatitis A and hepatitis B combination vaccine is recommended for all persons 18 years of age or older who are at risk of infection from their jobs, behaviours, or travel to certain areas. This includes military personnel, persons living in or moving to areas with high rates of hepatitis infection, and males who have sex with males.
The hepatitis B vaccine is generally safe and protective, with mild side effects that do not require medical attention. The most common side effects include redness and pain at the injection site, as well as fever and skin rash. These side effects typically go away during treatment as the body adjusts to the medicine. However, it is important to consult a doctor or nurse if any unusual or persistent side effects occur.
The hepatitis A and hepatitis B combination vaccine is safe and highly effective, even for individuals with compromised immune systems. Millions of doses of the hepatitis A vaccine have been administered since it was first licensed in 1995. While the vaccine is generally effective in preventing infection, it may not protect everyone who receives it. It is important to complete the vaccine dosing schedule and follow-up with a doctor to ensure the vaccine is working properly.
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Frequently asked questions
The Hepatitis A and B combination vaccine is administered to prevent infection caused by all known subtypes of the Hepatitis A and Hepatitis B viruses. It is recommended for individuals over the age of 18 who are at a higher risk of contracting the viruses.
The vaccine is recommended for individuals over the age of 18 who are at an increased risk of contracting Hepatitis A and B. This includes people with chronic liver disease, those who are pregnant or planning to become pregnant, and travellers to certain areas.
The combination vaccine is given by injection into the muscle and is typically administered in three separate doses over a six-month period. An accelerated schedule of four doses over one month, followed by a booster after one year, is also available for travellers.
Common side effects are mild and include redness and pain at the injection site, where a small lump may appear. Feeling faint or tired, or a headache may also occur. Severe side effects are rare but may include allergic reactions and seizures.











































