
Vaccines have long been a topic of debate, with some people questioning their value and whether the benefits outweigh the risks. Vaccines are one of the world's greatest public health achievements, providing strong immunity against diseases that can cause serious long-term health issues or even death. They also help prevent disabilities and save money by preventing diseases that are cheaper to prevent than treat. While any medicine can cause side effects, severe adverse reactions to vaccines are rare, and the risk of serious illness from the disease is typically much higher. Vaccinated people also help protect those who cannot get vaccinated or are at high risk from complications, a concept known as herd immunity. Despite this, some concerns have been raised about potential long-term adverse effects, such as an increased risk of diabetes, and the presence of thimerosal, a mercury-based preservative, in some vaccines. However, the best scientific evidence shows that thimerosal does not cause autism or other harmful effects, and the form of mercury known to be dangerous has never been used in vaccines.
| Characteristics | Values |
|---|---|
| Vaccines save lives | Vaccines have been proven to save lives, reducing the risk of critical illness and hospitalisation. |
| Vaccines protect against serious diseases | Vaccines help prevent serious and deadly diseases such as measles, flu, HPV, and hepatitis B. |
| Vaccines are safe and effective | Vaccines are rigorously tested and approved to ensure safety. Short-term side effects are typically mild and transient, while the risks of not vaccinating are much higher. |
| Vaccines are cost-effective | Vaccination is a cost-effective way to save lives and reduce the economic burden of diseases on individuals, families, and society. |
| Vaccines protect vulnerable individuals | Vaccination helps protect vulnerable individuals who cannot be vaccinated, including infants and older adults. |
| Vaccines are required for travel and certain activities | Many countries require proof of vaccination for travel. Vaccines may also be mandatory for school, work, and other activities to protect public health. |
| Vaccines reduce the burden on healthcare systems | Vaccines help reduce the number of hospitalisations and critical illnesses, easing the strain on healthcare resources. |
| Vaccines provide long-term protection | Vaccines can offer nearly lifelong protection against certain diseases, such as measles. |
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What You'll Learn

Vaccines reduce the risk of severe illness and hospitalisation
Vaccination is a proven method of reducing the risk of severe illness and hospitalisation. Vaccines have been shown to be highly effective in preventing serious complications from infectious diseases, which can affect anyone, regardless of age or health status.
In the context of COVID-19, vaccines have played a crucial role in mitigating the impact of the virus. For adults aged 18 and older, the 2023–2024 COVID-19 vaccines reduced the risk of critical illness and hospitalisation by significant margins in the first 2 months after vaccination. While protection decreased over time, the vaccines continued to offer some level of defence against severe illness and hospitalisation even after 4–6 months.
The benefits of COVID-19 vaccination extend beyond individual protection. Maternal vaccination during pregnancy has been found to reduce the risk of COVID-19-related hospitalisation in infants by around 54% in their first 3 months of life. Additionally, COVID-19 vaccination can help protect older adults, who are at a higher risk of severe illness and hospitalisation from COVID-19, with a 50% reduced risk of hospitalisation in the first 2 months after vaccination.
Vaccines against other diseases also demonstrate their effectiveness in reducing severe illness and hospitalisation. For instance, the measles vaccine has been a cornerstone of public health, providing nearly lifelong protection against a virus that historically killed about one in a thousand children infected. The measles, mumps, and rubella (MMR) vaccine has drastically reduced measles caseloads in the US since the late 1960s, showcasing the long-term impact of vaccination programmes.
Vaccines are a crucial tool in safeguarding public health and reducing the burden on healthcare systems. They offer a cost-effective way to prevent diseases, save lives, and reduce the social and economic impact of illnesses. By getting vaccinated, individuals not only protect themselves but also contribute to protecting their families, communities, and those who are unable to be vaccinated.
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Vaccines are rigorously tested and approved to ensure safety
After successful pre-clinical trials, vaccines undergo multiple phases of clinical trials with human participants. Phase I trials involve testing in small groups of adults, while Phase II expands to larger groups. Finally, Phase III involves thousands of participants and is critical for evaluating the vaccine's safety and effectiveness. During this phase, the FDA also inspects the manufacturing facilities to ensure reliable and consistent large-scale production.
Following a successful Phase III trial, the vaccine manufacturer applies for a license from the FDA or other regulatory bodies. The FDA thoroughly reviews the clinical trial data, assesses the need for the vaccine, and evaluates the manufacturing process and site. Even after approval, the FDA continues to monitor vaccine production activities, including regular inspections and lot testing, to ensure ongoing safety and compliance with regulations.
Phase IV studies are an essential part of vaccine testing that occurs after the vaccine is already in use. These studies provide long-term evaluation of the vaccine's safety and effectiveness in a broader population. Additionally, the CDC and FDA employ various systems, such as VAERS and VSD, to monitor vaccine safety and address any reported issues or adverse events. These measures help ensure that vaccines remain safe and successful even after they are recommended for public use.
The approval process for vaccines is robust and meticulous, prioritizing safety at every stage. By conducting thorough testing, inspections, and ongoing monitoring, regulatory agencies ensure that vaccines are safe and effective for the public. This rigorous process gives confidence that the benefits of vaccines greatly outweigh any potential risks.
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Vaccines are cost-effective and save lives
Vaccines are one of the most successful and cost-effective health interventions, saving and improving millions of lives each year. They are as important to our overall health as diet and exercise. Vaccines save lives by preventing diseases that can be extremely deadly and costly. For example, the COVID-19 pandemic has shown that vaccines are a crucial defence mechanism, averting millions of hospitalizations and deaths. In the US alone, the first six months of COVID-19 vaccinations prevented an estimated 8 million cases, 120,000 deaths, and 700,000 hospitalizations.
Vaccines are also cost-effective. Studies have found that every $1 spent on childhood immunizations results in a savings of approximately $11 to the US economy. In adults, an adult vaccination program can return up to 19 times its initial investment. In low- and middle-income countries, every $1 spent on immunization programs yields $52 in return.
Vaccines have nearly eradicated deadly diseases such as polio, and have significantly reduced the global infant mortality rate. Routine childhood immunizations are estimated to have prevented more than 1 million deaths in US children between 1994 and 2023. Vaccines also prevent long-term disabilities and strengthen local health services in remote places.
Vaccines are especially important for young and healthy people, as they can help them stay that way. Vaccine-preventable diseases can strike anyone at any time, and can be very expensive for individuals, families, and society as a whole. An average flu illness can last up to 2 weeks, with 5 or 6 missed work or school days. Adults who get hepatitis A lose an average of one month of work.
Vaccines are a safe and effective way to protect yourself and your community. They are recommended throughout your life to help protect against many infections and can be required for school, work, and travel.
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Vaccines protect vulnerable people who cannot be vaccinated
Vaccines have been proven to be beneficial in protecting against infections and diseases, and in some cases, they have been a matter of life and death. While some people may be unable to get vaccinated due to age or medical conditions, vaccines play a crucial role in protecting these vulnerable individuals.
Vaccines create a protective barrier around those who cannot be vaccinated by reducing the overall spread of diseases. For example, the measles vaccine has been highly effective in preventing outbreaks and reducing deaths. Dr. Peter Marks, a vaccine expert, emphasizes the benefits of the measles vaccine, stating that it provides nearly lifelong protection against a virus that kills about one in a thousand children. By vaccinating a significant portion of the population, the likelihood of unvaccinated individuals encountering the disease decreases, thereby safeguarding them from potential harm.
Vaccines also protect vulnerable people who cannot develop immunity on their own. Newborns, for instance, rely on their mothers' immunity during their early stages of life. Pregnant individuals who receive recommended vaccines, such as the measles, mumps, and rubella vaccines, help protect their unborn children. Additionally, individuals with weakened immune systems, such as those undergoing cancer treatment or suffering from long-term effects of COVID-19, may not be eligible for certain vaccines. In such cases, the vaccination of their community members becomes crucial in creating a protective shield around them.
Furthermore, vaccines are essential in preventing the spread of diseases to vulnerable individuals who cannot be vaccinated due to underlying medical conditions. For instance, adults with hepatitis A may miss up to a month of work, affecting their ability to care for their dependents. By vaccinating those who can be vaccinated, the risk of disease transmission to vulnerable individuals is significantly reduced. This not only protects the health of the vulnerable but also ensures the well-being of their loved ones.
In conclusion, vaccines play a critical role in safeguarding vulnerable people who cannot be vaccinated. They achieve this by reducing disease transmission, protecting those with weakened immune systems, and enabling community members to care for their vulnerable loved ones. By vaccinating those who can be vaccinated, we create a protective barrier that helps shield the most vulnerable members of our society from preventable diseases and potential harm.
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Vaccines help prevent the spread of contagious diseases
Vaccines are one of the best ways to prevent the spread of contagious diseases. They work by imitating an infection, causing the body's immune system to produce antibodies and learn how to defend itself from a particular disease without the dangers of a full-blown infection. This process, known as immunization, results in active immunity, which is a longer-lasting form of protection compared to passive immunity.
Vaccines have been proven to be highly effective in preventing the spread of contagious diseases. For instance, the measles vaccine has been shown to provide nearly lifelong protection against a virus that kills about one in a thousand children who contract it. Similarly, the measles vaccine has made measles outbreaks in the US relatively rare, with only around 700 cases reported in a year, a remarkable achievement considering the high contagiousness of the disease.
Vaccines are also cost-effective, saving lives while reducing the economic burden on individuals, families, and society as a whole. Studies have found that every $1 spent on childhood immunizations results in a savings of approximately $11 to the US economy. Vaccines also help reduce the number of missed workdays, enabling people to care for their families and contribute to their communities.
Furthermore, vaccines are recommended throughout life to protect against various infections. Routine childhood immunizations are crucial, and it is important for children and adolescents to catch up on any missed vaccines as soon as possible. Adults should also stay up to date with recommended vaccines, such as tetanus boosters, seasonal flu, and COVID-19 vaccines, to protect themselves and those around them.
Overall, vaccines play a vital role in preventing the spread of contagious diseases, saving lives, reducing societal costs, and contributing to the overall health and well-being of individuals and communities.
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Frequently asked questions
Vaccines protect against diseases that can cause serious long-term health problems or death. They also help prevent disabilities such as blindness and paralysis that can be caused by disease. Vaccines have saved more lives than any other medical intervention, including antibiotics or surgery.
Any medicine can cause side effects, but serious side effects from vaccines are very rare. Adverse reactions to vaccines are generally mild, and severe events resulting in death or permanent damage are rare. In one study, it was found that immunisation starting after the age of 2 months is associated with an increased risk of diabetes.
Vaccines provide strong, often life-long immunity without causing infection. Getting sick comes with risks for complications. For example, the risk of encephalitis (brain infection or swelling) from measles is 1 in 1,000, and the risk of pneumonia with measles is 1 in 20. In comparison, the risk of a serious allergic reaction from the measles vaccine is 1 in 1 million. Vaccinated people also help protect those who are not vaccinated through "herd immunity" or "community immunity".
Yes, vaccines save money. It is cheaper to prevent a disease than to treat it. For all the children born in the U.S. in one year, routine immunisation saves more than $63.6 billion in societal and healthcare costs across their lifetime.











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